The HPV E2 Transcriptional Transactivation Protein Stimulates Cellular DNA Polymerase Epsilon
The papillomavirus (PV) protein E2 is one of only two proteins required for viral DNA replication.E2 is the viral transcriptional regulator/activation protein as well as the initiator of viral DNA replication.E2 is known to interact with various cellular DNA replication proteins, including the PV E1 protein, the cellular ssDNA binding complex (RPA)